首次提出了刚性大环类分子环[6]芳酰胺萃取剂在分子内三中心氢键导向下借助远程位阻效应成环的动力学机制，实现了对Cs⁺的有效萃取(J. Am. Chem. Soc. 2011)；发现非聚集型环[6]芳酰胺对镧系离子和锕系Th⁴⁺具有很高的络合萃取能力(J. Incl. Phenom. Macrocycl. Chem.)以及非环芳酰胺对过渡金属离子Hg²⁺的选择性萃取(J. Hazard. Mater., 2012)；基于镧-锕系离子中Th⁴⁺的荧光分子探针被首次文献报道（Chin. J. Chem., 2013）。

 

      将CMPO、酰胺荚醚/硫代酰胺荚醚或冠醚基团引入杯芳烃预组织性平台用于高放废液后处理的萃取剂，实现了An/Ln组分离或Cs⁺分离萃取，已在中国原子能院进行了Am³⁺/Eu³⁺分离萃取热实验研究，并从理论上揭示了在分子设计中CMPO-杯[4]芳烃间隔基作为分离次级因素的重要性。

 

      建立了放射性核素⁹⁸Tc的一种新的拥有自主知识产权的分离与纯化方法，成功解决了从常量钼中分离提纯ng级⁹⁸Tc等关键技术难题，并通过对制靶、辐照、分析测量、放射化学分离等关键技术的研究，获得了^178m2Hf 同核异能素，满足了国防科研和国土资源勘查等领域的需求。
      先后承担国家自然科学基金重大研究计划、面上项目、四川省科技支撑计划等科研项目20多项，获四川省科技进步二等奖1项，在包括J. Am. Chem. Soc.、Chem. Commun.、Dalton Trans.、J. Hazard. Mater.等国内外高水平刊物发表论文70余篇，发表论文SCI他人应用超过400次，获准国家发明专利7项。

附研究成果：
一、获奖情况：
1.   刘 宁、杨远友、廖家莉、廖小东、金建南、曹养书、杨朝文，基于回旋加速器的新型同位素研制与应用，2013年四川省科技进步二等奖
二、2009-2014代表性论文
1.Lei Wu; Yuyu Fang; Yiming Jia; Yuanyou Yang; Jiali Liao; Ning Liu; Xinshi Yang; Wen Feng*; Jialin Ming and Lihua Yuan*, Pillar[5]arene-based diglycolamides for highly efficient separation of americium(III) and europium(III), Dalton Trans., 2014, 43(10), 3835–3838.
2.Hongzhu Chu; Lutao He; Qian Jiang; Yuyu Fang; Yiming Jia; Xiangyang Yuan; Shuliang Zou; Xianghui Li; Wen Feng*; Yuanyou Yang; Ning Liu; Shunzhong Luo; Yanqiu Yang; Liang Yang; Lihua Yuan*, CMPO-calix[4]arenes with spacer containing intramolecular hydrogen bonding: effect of local rigidification on solvent extraction towards f-block elements, J. Hazard. Mater., 2014, 264, 211-218.
3.Bo Li; Lijian Ma; Yin Tian; Xiaodan Yang; Juan Li; Chiyao Bai; Xiaoyu Yang; Shuang Zhang; Shoujian Li* and Yongdong Jin*, A catechol-like phenolic ligand-functionalized hydrothermal carbon: One-pot synthesis, characterization and sorption behavior toward uranium, J. Hazard. Mater., 2014, 271, 41–49.
4.Jinchuan Hu; Long Chen; Jie Shen; Jian Luo; Pengchi Deng; Yi Ren; Huaqiang Zeng; Wen Feng*; and Lihua Yuan*, Convergent heteroditopic cyclo[6]aramides as macrocyclic ion-pair receptors for constructing [2]pseudorotaxanes, Chem. Commun., 2014, 50(59), 8024 – 8027.
5.Yan Li; Yiming Jia; Zhenwen Wang; Xianghui Li; Wen Feng; Pengchi Deng*; Lihua Yuan*, An insight into extraction of transition metal ions by picolinamides associated with intramolecular hydrogen bonding and rotational isomerization, RSC Adv., 2014, 4, 29702–29714.
6.Ning Pan; Debin Guan; Yuntao Yang; Zhenling Huang; Ruibing Wang; Yongdong Jin; Chuanqin Xia*, A rapid low-temperature synthetic method leading to large-scale carboxyl graphene[J]. Chem. Eng. J., 2014, 236, 471-479.
7.Jinghui Zeng, Xia Yang, Jiali Liao, Ning Liu, Yuanyou Yang, Zhifang Chai, Dongqi Wang, A computational study on the complexation of Np(V) with TMOGA and its carboxylate analogs, Physical Chemistry Chemical Physics, 2014,16(31):16536-16546
8.Yiming Jia; Yuyu Fang; Yan Li; Lutao He; Wenhua Fan; Wen Feng*; Yuanyou Yang; Jiali Liao; Ning Liu; Lihua Yuan*, Pillar[5]arenes bearing phosphine oxide pendents as Hg2+ selective receptors, Talanta, 2014, 125, 322–328.
9.Huang Huang, Songdong Ding*, Ning Liu, Yuxuan Wu, Dongping Su and Song Huang, Extraction of trivalent americium and europium from nitric acid solution with a calixarene-based diglycolamide, Sep. Purif. Technol., 2014, 123, 235–240.
10.Huang Huang, Songdong Ding*, Dongping Su, Ning Liu, Jieru Wang, Mengling Tan and Jianen Fei, High selective extraction for thorium(IV) with NTAamide in nitric acid solution: Synthesis, solvent extraction and structure studies, Sep. Purif. Technol., 2014, 138, 65–70.
11.Tu Lan, Yue Feng, Jiali Liao, Xiaolong Li, Congcong Ding, Dong Zhang, Jijun Yang, Junhui Zeng, Yuanyou Yang, Jun Tang, Ning Liu, Biosorption behavior and mechanism of cesium-137 on Rhodosporidium fluviale strain UA2 isolated from cesium solution, J. Environ. Radioactiv, 2014, 134, 6-13
12.Xiaolong Li, Congcong Ding, Jiali Liao, Tu Lan, Feize Li, Dong Zhang, Jijun Yang, Yuanyou Yang, Shunzhong Luo, Jun Tang, Ning Liu, Biosorption of Uranium on Bacillus sp. dwc-2：Preliminary Investigation on Mechanism, J. Environ. Radioactiv, 2014, 135: 6-12.
13.Lutao He; Qian Jiang; Rongzhao Gao; Xinshi Yang; Wen Feng*; Shunzhong Luo; Yanqiu Yang; Liang Yang; Lihua Yuan, Crescent aromatic oligothioamides as highly selective receptors for copper(II) ion, Sci. China Chem., 2014, 57(9), 1246-1256.
14.Zhongyong Zha; Dingna Wang; Wei Hong; Li Liu; Sai Zhou; Xiaojie Feng; Bing Qin; Jianmei Wang; Yi Yang; Liang Du; Dong Zhang; Zhendong Fang; Chuanqin Xia*, Influence of Europium speciation on its accumulation in Brassica napus and over-expressing BnTR1 lines. J. Radioanal. Nucl. Chem., 2014, 301(1), 257-262.
15.Congcong Ding, Su Feng, Xiaolong Li, Jiali Liao, Yuanyou Yang, Zhu An, Qiqi Wu,  Dong Zhang, Jijun Yang, Jun Tang, Jie Zhang, Ning Liu, Mechanism of thorium biosorption by the cells of the soil fungal isolate Geotrichum sp. dwc-1, Radiochimca Acta, 2014, 102(1-2): 175-184.
16.Yuyu Fang; Lei Wu; Jiali Liao; Long Chen; Yuanyou Yang; Ning Liu; Lutao He; Shuliang Zou; Wen Feng* and Lihua Yuan*, Pillar[5]arene-based phosphine oxides: novel ionophores for solvent extraction separation of f-block elements from acidic media，RSC Adv., 2013, 3, 12376-12383.
17.Jun Liu; Juan Li; Xiaodan Yang; Qiang Song; Chiyao Bai; Yong Shi; Lan Zhang; Chunxia Liu; Shoujian Li* and Lijian Ma*, Facile preparation of polyphenolic hydroxyl functionalized uranium-selective chelating sorbent: simple oxidation of styrene–divinylbenzene copolymer microparticles by Hummers method, Mater. Lett., 2013, 97, 177–180.
18.Ning Pan, Jianguo Deng, Debin Guan, Yongdong Jin, Chuanqin Xia*, Adsorption characteristics of Th (IV) ions on reduced graphene oxide from aqueous solutions[J]. Appl. Surf. Sci., 2013, 287, 478-483.
19.Jinchuan Hu; Long Chen; Yi Ren; Pengchi Deng; Xiaowei Li; Youjia Wang; Yiming Jia; Jian Luo; Xinshi Yang; Wen Feng* and Lihua Yuan*, Nonaggregational Shape-Persistent Cyclo[6]aramide and Its Macrocyclic Effect toward Binding Secondary Ammonium Salts in Moderately Polar Media, Org. Lett., 2013, 15 (18), 4670–4673.
20.Lutao He; Qian Jiang; Yiming Jia; Yuyu Fang; Shuliang Zou; Yuanyou Yang; Jiali Liao; Ning Liu; Wen Feng*; Shunzhong Luo; Yanqiu Yang; Liang Yang and Lihua Yuan, Solvent extraction of thorium(IV) and rare earth elements with novel polyaramide extractant containing preorganized chelating groups, J. Chem. Technol. Biotechnol., 2013, 88(10),1930–1936.
21.Qian Jiang; Lu-Tao He; Shun-Zhong Luo, Yan-Qiu Yang, Liang Yang, Wen Feng* and Li-Hua Yuan, Synthesis of a crescent aromatic oligothioamide and its highly selective recognition towards copper(II) ions, Chin. Chem. Lett., 2013, 24(10), 881-884
22.Rongzhao Gao; Jinchuan Hu; Ke Zhang; Youzhou He; Peng Liu; Shunzhong Luo; Yanqiu Yang; Liang Yang; Wen Feng*; Lihua Yuan, Highly Selective Fluorescent Recognition towards Th4+ Based on Coumarin-derivatized Crescent Aromatic Oligoamide, Chin. J. Chem., 2013, 31 (5), 689-694.
23.Xingliang Li; Wanjun Mu; Bijun Liu, Wenbin Zhong, Hongyuan Wei, Yuan Jian, Zhengkun Zhong, Shunzhong Luo and Shoujian Li*, Adsorption kinetic, isotherm and thermodynamic studies of Sr2+ onto hexagonal tungsten oxide, J. Radioanal. Nucl. Chem., 2013, 298, 47–53.
24.Ning Pan; Debin Guan; Ting He; Ruibing Wang; Wyman, I.; Yongdong Jin and Chuanqin Xia*, Removal of Th4+ ions from aqueous solutions by graphene oxide. J. Radioanal. Nucl. Chem., 2013, 298, 1999-2008.
25.Xianghui Li, Yiming Jia, Yi Ren, Youjia Wang, Jinchuan Hu, Teng Ma, Wen Feng and Lihua Yuan*, Quadruply hydrogen-bonded heteroduplexes based on imide and urea units arrayed with ADDA/DAAD sequence, Org. Biomol. Chem., 2013, 11, 6975-6983
26.Xinshi Yang, Long Chen, Yongan Yang, Youzhou He, Shuliang Zou, Wen Feng*, Yuanyou Yang, Ning Liu, Jiali Liao, Lihua Yuan*, Synthesis of crescent aromatic oligoamides with preorganized chelating groups and their extraction towards transition metal ions, J. Hazard. Mater., 2012, 217-218, 171-176.
27.Hang Wang, Lijian Ma, Kecheng Cao, Junxia Geng, Jun Liu, Qiang Song, Xiaodan Yang and Shoujian Li*, Selective solid-phase extraction of uranium by salicylideneimine-functionalized hydrothermal carbon, J. Hazard. Mater., 2012, 229, 321-330
28.Xusong Pan, Chao Chen, Jiang Peng, Yongan Yang, Yinghan Wang, Wen Feng*, Pengchi Deng* and Lihua Yuan*; Supramolecular graft copolymers in moderately polar media based on hydrogen-bonded aromatic oligoamide units, Chem. Commun., 2012, 48(76), 9510-9512.
29.Qiang Song, Lijian Ma, Jun Liu, Chiyao Bai, Junxia Geng, Hang Wang, Bo Li, Liyue Wang and Shoujian Li*, Preparation and adsorption performance of 5-azacytosine-functionalized hydrothermal carbon for selective solid-phase extraction of uranium, J. Colloid Interf. Sci., 2012, 386, 291–299.
30.Shuliang Zou, Lutao He, Jing Zhang, Youzhou He, Lihua Yuan,* Lixin Wu,* and Wen Feng;Tunable Mesogens Based on Shape-Persistent Aromatic Oligoamides: From Lamellar, Columnar, to Nematic Liquid Crystalline Phase, Org. Lett., 2012, 14 (14), 3584–3587.
31.Lijian Zhong, Long Chen, Wen Feng, Shuliang Zou, Yuanyou Yang, Ning Liu, Lihua Yuan*; Shape-persistent macrocycles: efficient extraction towards lanthanide and actinide elements, J. Incl. Phenom. Macrocycl. Chem., 2012, 72, 367-373.
32.Hongle Liu, Xusong Pan, Lihua Yuan, Shuliang Zou, Peishen Li, Wei Wang, Youzhou He, Wen Feng*, Xiaoyong Yang*, Kai Luo, Yong Wu, Direct Perfluorination of An Acid-Sensitive Glycol Ether as Precursor for Perfluoro (2-(methoxymethoxy)ethyl vinyl ether), Synthetic Commun., 2012, 42, 959–966.
33.Yongan Yang, Wen Feng, Jinchuan Hu, Shuliang Zou, Rongzhao Gao, Kazuhiro Yamato, Mark Kline, Zhonghou Cai, Yi Gao, Yibing Wang, Yibao Li, Yanlian Yang, Lihua Yuan*, Xiaocheng Zeng*, Bing Gong*, Well-Defined Nanotubular Assemblies from Strong, Anisotropic Aggregation of Aromatic Oligoamide Macrocycles, J. Am. Chem. Soc., 2011, 133(46), 18590-18593.
34.Lu Zhang, Juan Du, Li Hua Yuan, Dong Zhang, Gui Ping Dan, Yuan You Yang, Wen Feng*, Synthesis of novel calixcrown derivatives with selective complexation towards cesium ions, Chin. Chem. Lett., 2011, 22, 284–287.
35.Shuqiong Li, Zhen Chen, Yongdong Jin, Shuihua Chen, Hang Wang, Junxia Geng, Qiang Song, Xiaodan Yang, Lijian Ma, Shoujian Li*, Zhi Qin* and Chong Zheng, A new approach for preparation of magnetiteegraphite composite: Intercalation of polyhydroxy iron cation into graphite oxide in L-arginine medium, Solid State Sci., 2011, 13, 862-866.
36.Zhen Chen, Lijian Ma, Shuqiong Li, Junxia Geng, Qiang Song, Jun Liu, Chunli Wang, Hang Wang, Juan Li, Zhi Qin and Shoujian Li∗, Simple approach to carboxyl-rich materials through low-temperature heat treatment of hydrothermal carbon in air, Appl. Surf. Sci., 2011, 257, 8686–8691
37.Jishen Zeng, Wei Wang, Pengchi Deng, Wen Feng, Jingjing Zhou, Yuanyou Yang, Lihua Yuan*, Kazuhiro Yamato, Bing Gong*, Interplay of Olefin Metathesis and Multiple Hydrogen Bonding Interactions: Covalently Cross-linked Zippers, Org. Lett., 2011, 13 (15), 3798–3801.
38.Xianghui Li, Yuyu Fang, Pengchi Deng, Wen Feng, Jingchuan Hu, Tian Li, Lihua Yuan*; Self-Complementary Quadruply Hydrogen-Bonded Duplexes Based on Imide and Urea Units, Org. Lett., 2011, 13 (17), 4628–4631.
39.Penghui Zhang, Hongzhu Chu, Xianghui Li, Wen Feng, Pengchi Deng, Lihua Yuan*, and Bing Gong, Alternative Strategy for Adjusting the Association Specificity of Hydrogen-Bonded Duplexes, Org. Lett., 2011, 13(1),54-57.
40.Lihua Yuan*, Penghui Zhang, Wen Feng, Bing Gong*, Hydrogen-Bonded Oligoamide Duplexes as Programmable Molecular Recognition Units: A Systematic Approach Towards Directed Self-Assembly and Controlled Non-Covalent Synthesis, Curr. Org. Chem. 2011, 15(9), 1250-1265.
41.Ruikai Cao, Jingjing Zhou, Wei Wang, Wen Feng, Xianghui Li, Penghui Zhang, Pengchi Deng, Lihua Yuan*, and Bing Gong*, Oligoamide Duplexes as Organogelators, Org. Lett., 2010, 12(13), 2958-2961.
42.Zhengchuan Feng, Zheng Zhang,  Lihua Yuan, Wen Feng*, Zhen Huang*, Synthesis of Thymidine Derivatives Bearing Aromatic Oligoamides with Rigidified Backbone, Heterocycl. Commun., 2010, 16(4-6), 269-273.
43.Wen Feng, Kazuhiro Yamato, Liuqing Yang, Joseph S. Ferguson, Lijian Zhong, Shuliang Zou, Lihua Yuan,*, Xiao Cheng Zeng,*,and Bing Gong*, Efficient Kinetic Macrocyclization, J. Am. Chem. Soc., 2009, 131, 2629-2637.
44.Liuqing Yang, Lijian Zhong, Kazuhiro Yamato, Xiaheng Zhang, Wen Feng, Pengchi Deng, Lihua Yuan,* Xiao Cheng Zeng* and Bing Gong*, Aromatic oligoamide macrocycles from the bimolecular coupling of folded oligomeric precursors, New J. Chem., 2009, 33, 729–733.
45.Shuliansg Zou, Youzhou He, Yongan Yang, Yi Zhao, Lihua Yuan, Wen Feng,* Kazuhiro Yamato, Bing Gong*, Improving the Efficiency of Forming ‘Unfavorable’ Products: Eight-Residue Macrocycles from Folded Aromatic Oligoamide Precursors, Synlett, 2009, 9, 1437-1440.
46.Jiaojiao Wu, Bing Li, Jiali Liao, Yue Feng, Dong Zhang, Jun Zhao, Wei Wen, Yuanyou Yang, Ning Liu, Behavior and analysis of Cesium adsorption on montmorillonite mineral, J. Environ. Radioactiv, 2009, 100(10): 914-920.
三、发明专利
1.冯文、方玉宇、袁立华、吴雷、陈龙，一种氧化膦修饰的柱[5]芳烃衍生物及其应用， ZL 201310033390.8.
2.袁立华、吴雷、冯文、方玉宇、杨心师，一种酰胺荚醚修饰的柱[5]芳烃衍生物及其制备方法和应用，ZL 201310550276.2
3.杨远友、刘宁、廖家莉,制取放射性核素95m/97mTC的方法，ZL 201310286362.7
4.丁颂东，吴宇轩，刘宁，黄松，黄璜，苏冬萍，王洁茹，谈梦玲 二酰胺荚醚萃取剂的合成方法，ZL201210468561.5, 2013. 3. 27.
5.袁立华、钟利健、冯文、陈龙，含三中心氢键的环芳酰胺萃取剂在分离稀土元素中的应用，ZL 201010595583.9.
6.杨远友、刘宁、廖家莉，一种新的制取放射性核素98TC的方法，ZL 2010 1 0174356.9.
7.袁立华、冯文、岳亚荣、张鹏辉、张路、杨永安、蒲文臣，2,7-二羟基-3,6-萘二酸的制备方法，、ZL 200910167604.4.